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Daily PrEP is the most commonly prescribed PrEP regimen in Australia. Daily use of TD*/FTC is highly efficacious at preventing HIV transmission in MSM (1, 2), heterosexuals (3), transgender women (4) and people who inject drugs (PWID) (5) in the setting of high medication adherence. A detailed review of these and other studies that have demonstrated the efficacy and effectiveness of daily PrEP is beyond the scope of these guidelines. For more information see PrEP efficacy.

The ASHM PrEP Guidelines Panel continues to recommend that daily TD*/FTC should be offered to all populations at risk of HIV infection.